T1 Mapping for Myocardial Fibrosis by Cardiac Magnetic Resonance Relaxometry—A Comprehensive Technical Review
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Strudwick, Mark W
Galloway, Graham J
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Abstract
Cardiac magnetic resonance (CMR) imaging has been widely used to assess myocardial perfusion and scar and is the non-invasive gold standard for identification of focal myocardial fibrosis. However, the late gadolinium enhancement technique is limited in its accuracy for absolute quantification and assessment of diffuse myocardial fibrosis by technical and pathophysiological features. CMR relaxometry, incorporating T1 mapping, has emerged as an accurate, reproducible, highly sensitive, and quantitative technique for the assessment of diffuse myocardial fibrosis in a number of disease states. We comprehensively review the physics behind CMR relaxometry, the evidence base, and the clinical applications of this emerging technique.
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Frontiers in Cardiovascular Medicine
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3
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© 2017 Hamilton-Craig, Strudwick and Galloway. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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Hamilton-Craig, CR; Strudwick, MW; Galloway, GJ, T-1 Mapping for Myocardial Fibrosis by Cardiac Magnetic Resonance Relaxometry - A Comprehensive Technical Review, Frontiers in Cardiovascular Medicine, 2017, 3, pp. 00049