Can a digital twin of the residuum improve bionic solutions for individuals suffering from limb loss?

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Frossard, Laurent A
Langton, Christian M
Barrett, Rod S
Lloyd, David G
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2022
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Sydney, Australia

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Abstract

Introduction: Rehabilitation specialists need to improve differential diagnosis of the neuromusculoskeletal health issues of the residuum experienced by former and active Service Members suffering from limb loss1. The development of a portable and non-invasive diagnostic device seeks to help maintain residuum health and support bionic solutions. Here, we outline the latest developments of an In-vivo Kinetic system 2.0 (Fig. 1), a diagnostic device that combines: •Measurements of the mechanical loading applied to the site of amputation using portable wireless sensors2,

•Measurement of the tissue distribution within the residuum made by the newly developed Dynamic Anatomical Ultrasonography,

•Neuromusculoskeletal modelling or “digital twinning” of the residuum for a real-time personalized animation of the residuum during static and dynamic loading conditions3.

Technology readiness levels (TRL) were estimated at 7, 2, and 4 for the loading, ultrasound, and modelling parts, respectively. Thus, demonstrating feasibility to develop an integrated, wearable and non-invasive In-vivo Kinetic system 2.0 capable of performing patient-specific differential diagnosis of residuum health under real world conditions4.

However, barriers inherent to biosensors (e.g., ultrasound measurements, synchronisation), the creation of a digital twin (e.g., tissues mechanical property) and integration (e.g., discrepancies of TRLs) continue to be challenging. The clinical roll-out of the device will require overcoming these issues and consideration of discrepancies between the skills of practitioners and siloed health care organizations.

Discussion/future directions: This system will provide unparalleled holistic insight into residuum health and productively disrupt the current model of health care. Hopefully, this diagnostic device will facilitate restoration of mobility, return to active duty, and, ultimately, improve life of the growing population suffering from limb loss considering bionic solutions.

Acknowledgements: This work was supported by the FY19 Defense Medical Research and Development Program through the Joint Program Committee 8 / Clinical and Rehabilitative Medicine Research Program Restoring Warfighters with Neuromusculoskeletal Injuries Research Award (RESTORE) under Award No. W81XWH2110215-DM190659. Opinions, interpretations, conclusions, and recommendations are those of the author and are not necessarily endorsed by the FY19 Defense Medical Research and Development Program.

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Journal of Science and Medicine in Sport

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25

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Allied health and rehabilitation science

Sports science and exercise

Electronic device and system performance evaluation, testing and simulation

Clinical sciences

Applied and developmental psychology

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Frossard, LA; Langton, CM; Barrett, RS; Lloyd, DG, Can a digital twin of the residuum improve bionic solutions for individuals suffering from limb loss?, Journal of Science and Medicine in Sport, 2022, 25, pp. S4-S5