Hypertension, Left Ventricular Hypertrophy, and Myocardial Ischemia

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Stanton, T
Dunn, FG
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2017
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Abstract

The risks associated with hypertension emerge through a series of complex interactions. Myocardial ischemia is the major contributor to this risk. The mechanisms driving ischemia reflect many of the key factors in hypertension, including endothelial and neurohumoral factors, fibrosis, and hemodynamics. Left ventricular hypertrophy and fibrosis are of fundamental importance and together with hemodynamics provide an optimal template for myocardial ischemia. Understanding the pathophysiology has aided a more rational management approach but challenges remain which, if surmounted, will have an impact on the morbidity and mortality caused by myocardial ischemia in patients with hypertension.

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Medical Clinics of North America

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101

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1

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Subject

Clinical sciences

Hypertension

Ischemia

Management

Mechanisms

Perfusion

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Citation

Stanton, T; Dunn, FG, Hypertension, Left Ventricular Hypertrophy, and Myocardial Ischemia, Medical Clinics of North America, 2017, 101 (1), pp. 29-41

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