Survival outcomes following aggressive treatment of oligometastatic breast cancer: a systematic review protocol
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Lisy, Karolina
Campbell, Jared
Perry, Gajen
Prasannan, Subhita
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Abstract
Review question/objective: The objective of this systematic review is to assess the effectiveness of aggressive treatment of oligometastatic breast cancer (OMBC) on survival outcomes by conducting a meta-analysis of current available evidence. More specifically, the objectives are to identify the effectiveness of intensified multidisciplinary treatment with aggressive locoregional therapies on survival time, five-year survival rates and disease free survival. The population is adult women (18 years and over) with OMBC defined as single or few (five or less) metastases limited to a single organ and the comparative group is conventional palliative treatment aimed at disease control. Secondary objectives to be assessed will be adverse outcomes associated with intensified treatment regimes.
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JBI Database of Systematic Reviews and Implementation Reports
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15
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8
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Clinical sciences
Nursing
Oncology and carcinogenesis
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Coombe, R; Lisy, K; Campbell, J; Perry, G; Prasannan, S, Survival outcomes following aggressive treatment of oligometastatic breast cancer: a systematic review protocol, JBI Database of Systematic Reviews and Implementation Reports, 2017, 15 (8), pp. 2013-2019