A distinct expression profile separates Turkish and Australian melanocytic naevi (Letter)
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Schaider, Helmut
Akalin, Taner
Turkmen, Meltem
Sturm, Rick
Lambie, Duncan
Karaarslan, Isil K
Soyer, H Peter
Ozdemir, Fezal
Gabrielli, Brian
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Abstract
Sir: Following the Clark model of melanoma progression, melanocytic naevi (MNs) are thought to be precursor lesions of melanomas. Although MNs have been described phenotypically and histologically,1-3 the biology and molecular features accompanying them remain puzzling. A major disadvantage in studying the biology of MNs is the complete absence of in-vitro and in-vivo models. Therefore, one approach to better define potential markers of MNs is the selection of candidate genes based on existing knowledge of genes known to be required for transformation into melanocytic tumours, and to probe for their tissue expression.
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Histopathology
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69
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1
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Clinical sciences
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Life Sciences & Biomedicine
Cell Biology
Pathology
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Fox, C; Schaider, H; Akalin, T; Turkmen, M; Sturm, R; Lambie, D; Karaarslan, IK; Soyer, HP; Ozdemir, F; Gabrielli, B, A distinct expression profile separates Turkish and Australian melanocytic naevi (Letter), Histopathology, 2016, 69 (1), pp. 151-154