Expression of Vascular Endothelial-Cadherin in Mucoepidermoid Carcinoma: Role in Cancer Development
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Dehghan, Arash
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Abstract
Mucoepidermoid carcinoma (MEC) accounts for 35% of all malignant salivary gland tumors. Previous investigations have shown that vasculogenic mimicry (VM) exists in many cancers which can be used as a prognostic factor of poor prognosis. Elevated expression level of vascular endothelial (VE)-cadherin has been implicated in cancer neovascularization, growth, and progression. The current study aimed to study the presence of VE-cadherin in VM channels and tumor cells in different grades of MEC.
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Journal of International Society of Preventive & Community Dentistry
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7
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6
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© 2017 Journal of International Society of Preventive and Community Dentistry. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
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Dentistry
Science & Technology
Life Sciences & Biomedicine
Dentistry, Oral Surgery & Medicine
Mucoepidermoid carcinoma
salivary gland tumors
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Irani, S; Dehghan, A, Expression of Vascular Endothelial-Cadherin in Mucoepidermoid Carcinoma: Role in Cancer Development, Journal of International Society of Preventive & Community Dentistry, 7 (6), pp. 301-307