Double spiral detection channel for on-chip chemiluminescence detection
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Kwok, Yien Chian
Nam-Trung, Nguyen
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Abstract
In this paper, we introduced a three-layered microchip that consists of a double spiral channel design for chemiluminescence (CL) detection and a passive micromixer to facilitate the mixing of reagents. The design with two overlapping spiral channels doubled the CL intensity emitted from the reaction as compared to the design with a single spiral channel. The addition of the passive micromixer improved the signal by 1.5 times. Luminol-based chemiluminescence reaction was used for the characterization of the device. This microchip was successfully tested with the determination of l-cysteine and uric acid.
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Sensors and Actuators B: Chemical
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169
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© 2012 Elsevier B.V.. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
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Subject
Atomic, molecular and optical physics
Analytical chemistry
Sensor technology (incl. chemical aspects)
Materials engineering
Microelectromechanical systems (MEMS)