Needleless connector decontamination for prevention of central venous access device infection: a pilot randomized controlled trial

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Author(s)
Rickard, Claire M
Flynn, Julie
Larsen, Emily
Mihala, Gabor
Playford, E Geoffrey
Shaw, Joanie
Keogh, Samantha
Ullman, Amanda
Zhang, Li
Gavin, Nicole
Kleidon, Tricia
Chopra, Vineet
McCarthy, Sandie
Rocha, Patricia Kuerten
Marsh, Nicole
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2020
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Abstract

Pilot randomized controlled trial (180 patients) of needleless connector decontamination. Central line-associated bloodstream infection occurred in 2% (1/61) of 70% isopropyl alcohol (IPA) wipe, 2% (1/59) of 70% IPA cap, and zero (0/58) infections in 2% chlorhexidine gluconate in 70% IPA wipe patients. Larger definitive trials are feasible and needed.

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American Journal of Infection Control

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© 2020 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.

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Subject

Nursing

Health services and systems

Public health

Clinical sciences

Epidemiology

Bacteremia

Catheter Related Infections

Catheterization, Central Venous

Chlorhexidine Gluconate

Isopropyl Alcohol

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Rickard, CM; Flynn, J; Larsen, E; Mihala, G; Playford, EG; Shaw, J; Keogh, S; Ullman, A; Zhang, L; Gavin, N; Kleidon, T; Chopra, V; McCarthy, S; Rocha, PK; Marsh, N, Needleless connector decontamination for prevention of central venous access device infection: a pilot randomized controlled trial, American Journal of Infection Control, 2020

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