The aim of this study was to compare estimates of prevalence of physical activity indicators and associated sociodemographic factors obtained from telephone and face-to-face interviews with adults. Data from a cross-sectional populationbased survey of adults living in Florianópolis, Santa Catarina State, Brazil was compared to data collected through the telephonic system VIGITEL. There was no significant difference between the results from telephone interviews (n = 1,475) and face-to-face interviews (n = 1,720) with respect to prevalence of sufficient leisure time physical activity (19.3% versus 15.5%, respectively), sufficient leisure time and/or commuting physical activity (35.1% versus 29.1%, respectively) and physical inactivity (16.2% versus 12.6%, respectively). Some differences were observed with respect to the sociodemographic factors associated with leisure time and/or commuting physical activity and physical inactivity. The two techniques yielded generally similar results with respect to prevalence and sociodemographic factors associated to physical activity indicators.