Muscle mass (MM) plays an important role in the physical function of hemodialysis patients; however, muscle mass measurement can be unreliable and expensive. In contrast, the measurement of physical function (PF) is simple and cheap and may serve as an alternative. Muscle mass measured with computed tomography (CT) was correlated with the physical function tests: the six-minute walk test (SMWT), handgrip strength (HGS), 5-sit to stand test (STS5), timed up and go test (TUGT), short physical performance battery (SPPB) and physical activity (The Godin-Shephard leisure-time physical activity questionnaire). Hand grip strength was strongly positively correlated with thigh muscular area (r=0.656, p=0.000); and weakly correlated with arm muscle area (r=0.396, p=0.002), SMWT (r=0.373. p=0.004); SPPB (r=0.269, p=0.041) and physical activity (r=0.323, p=0.013). Muscle mass was weakly negatively correlated with the TUGT (r=-0.235, p=0.076). Weak to moderate positive correlations were found between the thigh muscle area and the SPPB (r=0.339, p=0.009) and PA (r=0.293, p=0.025). Hand grip strength is an easy, rapid, and low-cost measurement that can give valuable information regarding muscle mass