A Review of Management of Clostridium difficile Infection: Primary and Recurrence
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Manji, Arif
Gregory-Miller, Kathleen
Lee, Christine
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Abstract
Clostridium difficile infection (CDI) is a potentially fatal illness, especially in the elderly and hospitalized individuals. The recurrence and rates of CDI are increasing. In addition, some cases of CDI are refractory to the currently available antibiotics. The search for improved modalities for the management of primary and recurrent CDI is underway. This review discusses the current antibiotics, fecal microbiota transplantation (FMT) and other options such as immunotherapy and administration of non-toxigenic Clostridium difficile (CD) for the management of both primary and recurrent CDI.
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Antibiotics
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4
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4
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© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Clinical Sciences
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Life Sciences & Biomedicine
Infectious Diseases
Pharmacology & Pharmacy
recurrence
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Vincent, Y; Manji, A; Gregory-Miller, K; Lee, C, A Review of Management of Clostridium difficile Infection: Primary and Recurrence, Antibiotics, 2015, 4 (4), pp. 411-423