Novel Cytotoxic thiodiketopiperazine derivatives from a Tilachlidium sp.

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Feng, YJ
Blunt, JW
Cole, ALJ
Munro, MHG
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2004
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Abstract

Three novel thiodiketopiperazine derivatives, T988 A, B, and C (1-3), were isolated from a Tilachlidium sp. Their structures were elucidated by spectroscopic analyses using various 1D and 2D NMR techniques. All the compounds showed potent cytotoxicity against cultured P388 leukemia cells.

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Journal of Natural Products

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67

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12

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© 2004 American Chemical Society. Self-archiving of the author-manuscript version is not yet supported by this publisher. The contents of this journal can be freely accessed online via the ACS web page [? months] after publication. Use hypertext link above to access the ACS website.

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Chemical sciences

Biological sciences

Biomedical and clinical sciences

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