The global hydrological cycle is vulnerable to changing climatic conditions, especially in developing regions, which lack abundant resources and management of freshwater resources. This study evaluates the impacts of climate change on the hydrological regime of the Chirah and Dhoke Pathan sub catchments of the Soan River Basin (SRB), in Pakistan, by using the climate models included in the NEX-GDDP dataset and the hydrological model HBV-light. After proper calibration and validation, the latter is forced with NEX-GDDP inputs to simulate a historic and a future (under the RCP 4.5 and RCP 8.5 emission scenarios) streamflow. Multiple evaluation criteria were employed to find the best performing NEX-GDDP models. A different ensemble was produced for each sub catchment by including the five best performing NEX-GDDP GCMs (ACCESS1-0, CCSM4, CESM1-BGC, MIROC5, and MRI-CGCM3 for Chirah and BNU-ESM, CCSM4, GFDL-CM3. IPSLCM5A-LR and NorESM1-M for Dhoke Pathan). Our results show that the streamflow is projected to decrease significantly for the two sub catchments, highlighting the vulnerability of the SRB to climate change.