Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components

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Author(s)
Tran, Trong D
Ogbourne, Steven M
Brooks, Peter R
Sanchez-Cruz, Norberto
Medina-Franco, Jose L
Quinn, Ronald J
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2020
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Abstract

Propolis is a natural resinous material produced by bees and has been used in folk medicines since ancient times. Due to it possessing a broad spectrum of biological activities, it has gained significant scientific and commercial interest over the last two decades. As a result of searching 122 publications reported up to the end of 2019, we assembled a unique compound database consisting of 578 components isolated from both honey bee propolis and stingless bee propolis, and analyzed the chemical space and chemical diversity of these compounds. The results demonstrated that both honey bee propolis and stingless bee propolis are valuable sources for pharmaceutical and nutraceutical development.

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International Journal of Molecular Sciences

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21

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14

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© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Other chemical sciences

Genetics

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Science & Technology

Life Sciences & Biomedicine

Physical Sciences

Biochemistry & Molecular Biology

Chemistry, Multidisciplinary

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Tran, TD; Ogbourne, SM; Brooks, PR; Sanchez-Cruz, N; Medina-Franco, JL; Quinn, RJ, Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components, International Journal of Molecular Sciences, 2020, 21 (14), pp. 4988

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