Socioeconomic disadvantage but not remoteness affects short-term survival in prostate cancer: A population-based study using competing risks

No Thumbnail Available
File version
Thomas, Audrey A
Pearce, Alison
Sharp, Linda
Gardiner, Robert Alexander
Chambers, Suzanne
Aitken, Joanne
Molcho, Michal
Baade, Peter
Griffith University Author(s)
Primary Supervisor
Other Supervisors
File type(s)

Aim: We examined how sociodemographic, clinical and area-level factors are related to short-term prostate cancer mortality versus mortality from other causes, a crucial distinction for this disease that disproportionately affects men older than 60 years. Methods: We applied competing risk survival models to administrative data from the Queensland Cancer Registry (Australia) for men diagnosed with prostate cancer between January 2005 and July 2007, including stratification by Gleason score. Results: The men (n = 7393) in the study cohort had a median follow-up of 5 years 3 months. After adjustment, remoteness and area-level disadvantage were not significantly associated with prostate cancer mortality. However, area-level disadvantage had a significant negative relationship with hazard of death from a cause other than prostate cancer within 7 years; compared with those living in the most advantaged areas, the likelihood of mortality was higher for those in the most disadvantaged (subhazard ratio [SHR] = 1.39; 95% CI, 1.01–1.90; P = 0.041), disadvantaged (SHR = 1.51; 95% CI, 1.14–2.00; P = 0.004), middle (SHR = 1.34; 95% CI, 1.02–1.75; P = 0.034) and advantaged areas (SHR = 1.44; 95% CI, 1.09–1.89; P = 0.009). Those with Gleason score of 7 and higher had a lower hazard of prostate cancer mortality if they were living with a partner, whereas those with lower Gleason scores and living a partner had lower hazards of other-cause mortality. Conclusions: Understanding why men living in more disadvantaged areas have higher risk of non-prostate cancer mortality should be a priority

Journal Title

Asia-Pacific Journal of Clinical Oncology

Conference Title
Book Title
Thesis Type
Degree Program
Publisher link
Patent number
Grant identifier(s)
Rights Statement
Rights Statement
Item Access Status

This publication has been entered into Griffith Research Online as an Advanced Online Version.

Access the data
Related item(s)

Oncology and carcinogenesis

Oncology and carcinogenesis not elsewhere classified

Persistent link to this record