In this study we investigate the impact of the introduction of a range of safety measures on road fatalities in Queensland. The results indicate that there was a significant structural break in the fatalities data that coincided with the introduction of a number of policy measures, notably the increased implementation of the Random Road Watch program, installation of speed cameras, and increased use of random breath testing. The effect of the structural break was to reduce the average number of fatalities per month by 7.64, a fall of some 22%. This overall reduction comprised a fall of 5.18 per month in fatalities among drivers, and a fall of 3.14 per month among other road users. These imply an increase of approximately 5 percentage points in the share of total road fatalities accounted for by the non-driving group.