Lamp based detection of sars-cov-2 with low-cost off-the-shelf components

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Sreejith, KR
Umer, M
Soda, N
Kasetsirikul, S
Shiddiky, MJA
Nguyen, NT
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2020
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Netherlands

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Abstract

This paper reports the design, development, and testing of a novel, yet simple and low-cost portable device for rapid SARS-CoV-2 detection. The device performs loop mediated isothermal amplification (LAMP) and provides visually distinguishable images of the fluorescence emitted from the samples. The device utilises an aluminium block embedded with a cartridge heater for isothermal heating of the sample and a single-board computer and camera for fluorescence detection. The device demonstrates promising results within 20 minutes using clinically relevant starting concentrations of the synthetic template.

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MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

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Classical physics

Nanotechnology

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Sreejith, KR; Umer, M; Soda, N; Kasetsirikul, S; Shiddiky, MJA; Nguyen, NT, Lamp based detection of sars-cov-2 with low-cost off-the-shelf components, MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 2020, pp. 1214-1215