Role of Medium-Chain Fatty Acids in Healthy Metabolism: A Clinical Perspective

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Huang, L
Gao, L
Chen, C
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2021
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Abstract

Medium-chain fatty acids (MCFAs) serve not only as an energy source but also regulate glucose and lipid metabolism. The unique transport and rapid metabolism of MCFAs provide additional clinical benefits over other substrates such as long-chain fatty acids (LCFAs) and have prompted interest in the use of MCFAs for treating metabolic and neurological disorders. This review focuses on the metabolic role of MCFAs in modulating cellular signaling and regulating key circulating metabolites and hormones. The potential of MCFAs in treating various metabolic diseases in a clinical setting has also been analyzed.

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Trends in Endocrinology and Metabolism

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32

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6

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Clinical sciences

glucose metabolism

lipid metabolism

medium-chain fatty acids

metabolic/neurological diseases

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Huang, L; Gao, L; Chen, C, Role of Medium-Chain Fatty Acids in Healthy Metabolism: A Clinical Perspective, Trends in Endocrinology and Metabolism, 2021, 32 (6), pp. 351-366

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