Aim To measure the relationship between patient participation in pressure injury prevention (PIP) both before and after implementing a patient-centred pressure injury prevention care bundle (PPIPCB). Methods This before and after intervention study used surveys to measure adult medical patients' participation in their PIP care and satisfaction with the PPIPCB across three medical inpatient units in an Australian tertiary hospital. Descriptive statistics described the sample and patient intervention satisfaction. A paired samples t-test measured changes in the before and after survey scale scores. Results Eighty patients, with an average age of 67.2 years (SD=18.3), were recruited during November and December 2019. There were statistically significant increases in total mean scores for the patient participation in pressure injury prevention (PPPIP) scale after the intervention (before: mean=18.6, SD=2.8; after: mean=22.5, SD=1.9). Significant improvements in patients' self-reported knowledge of pressure injury (PI) risk and perceived levels of participation in their PI care were reported after receiving the intervention. A total of 98.8% of participants agree or strongly agree that they were satisfied with the intervention as delivered. Conclusion Engaging patients is one way to increase their participation in PIP. Wider clinical adoption appears warranted, with nurses the key to the successful implementation.