Griffith Research Online: Recent submissions
Now showing items 1-20 of 105001
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Diet quality, protein-bound uraemic toxins and gastrointestinal microbiome in chronic kidney disease
(58th Congress of the European-Renal-Association (ERA)-European-Dialysis-and-Transplant-Association (EDTA), 2021)Background and Aims Individuals with chronic kidney disease (CKD) have significantly increased risk of cardiovascular mortality which is only partially explained by Framingham risk factors. There is a growing body of ...CONFERENCE OUTPUT -
Gut health interventions in chronic kidney disease: acceptability and feasibility of of synbiotic supplementation
(58th Congress of the European-Renal-Association (ERA)-European-Dialysis-and-Transplant-Association (EDTA), 2021)Background and Aims Synbiotics, co-administered prebiotics and probiotics, have emerged over the last decade as an innocuous intervention targeting the microbial generation of the uraemic toxins, indoxyl sulphate (IS) and ...CONFERENCE OUTPUT -
Antihypertensive drugs in the elderly - The evidence of benefit
(Cardiovascular Drugs and Therapy, 2001)Hypertension is a major cardiovascular risk factor. The commonest mode of death in the elderly is a cardiovascular one and so the treatment of hypertension in the elderly popuiation is an important clinical objective. The ...JOURNAL ARTICLE -
Fixed dose combination therapy in the treatment of hypertension
(Journal of Human Hypertension, 2002)Raised blood pressure is a common and quantitatively important cardiovascular risk factor. Over 50% of over 65’s in industrialised countries may be considered to have hypertension1 and 50% of people in this age group go ...JOURNAL ARTICLE -
Urgent in-patient coronary angiography: A comparison of centres with and without cardiac catheter facilities
(Scottish Medical Journal, 2006)Objectives: To review the referral of patients to a tertiary centre for urgent angiography and to determine if there are differences in invasive treatment strategies for patients with acute coronary syndrome (ACS). Methods: ...JOURNAL ARTICLE -
Variation at the beta-1 adrenoceptor gene locus affects left ventricular mass in renal failure
(Journal of Nephrology, 2002)Objectives: To examine the relationship between this variation in the β1AR gene and the effect on LV mass. Background: Left ventricular (LV) mass is an important cardiovascular risk factor. Beta-1 adrenoceptors (β1AR) are ...JOURNAL ARTICLE -
How should we optimize cardiac resynchronization therapy?
(European Heart Journal, 2008)Optimization of cardiac resynchronization therapy is increasingly performed. Numerous methods have been proposed, many being echocardiographic. Both the technique and the timing of optimization are contentious. Whether ...JOURNAL ARTICLE -
Hypertension and Myocardial Ischemia
(Medical Clinics of North America, 2009)There is an impressive evidence base for the presence of myocardial ischemia in patients who have hypertension. This relationship ranges from the obvious association with obstructive coronary artery disease to more subtle ...JOURNAL ARTICLE -
Association of Myocardial Deformation With Mortality Independent of Myocardial Ischemia and Left Ventricular Hypertrophy
(JACC: Cardiovascular Imaging, 2009)Objectives: The aim of this study was to investigate the relative contributions of left ventricular hypertrophy (LVH) and myocardial ischemia to the association between abnormal myocardial deformation during dobutamine ...JOURNAL ARTICLE -
Interaction and Prognostic Effects of Left Ventricular Diastolic Dysfunction and Patient-Prosthesis Mismatch as Determinants of Outcome After Isolated Aortic Valve Replacement
(American Journal of Cardiology, 2009)There are variable reported effects of patient-prosthesis mismatch (P-PM) on outcome. It was hypothesized that the adverse effect attributed to P-PM is actually due to left ventricular diastolic dysfunction (DD) in patients ...JOURNAL ARTICLE -
Prediction of all-cause mortality from global longitudinal speckle strain: Comparison with ejection fraction and wall motion scoring
(Circulation: Cardiovascular Imaging, 2009)Background-Although global left ventricular systolic function is an important determinant of mortality, standard measures such as ejection fraction (EF) and wall motion score index (WMSI) have important technical limitations. ...JOURNAL ARTICLE -
Interaction of Left Ventricular Geometry and Myocardial Ischemia in the Response of Myocardial Deformation to Stress
(American Journal of Cardiology, 2009)Myocardial deformation parameters are sensitive markers of global left ventricular (LV) systolic function, but their interaction with LV geometry is unknown. We sought to investigate the effect of LV geometry on myocardial ...JOURNAL ARTICLE -
Assessment of subendocardial structure and function
(JACC: Cardiovascular Imaging, 2010)The combination of high energy expenditure and the borderline adequacy of perfusion make the subendocardium uniquely vulnerable to injury. Selective subendocardial involvement is usually a marker of subclinical disease. ...JOURNAL ARTICLE -
Usefulness of at rest and exercise hemodynamics to detect subclinical myocardial disease in type 2 diabetes mellitus
(American Journal of Cardiology, 2011)Patients with type 2 diabetes mellitus (T2DM) might have subclinical myocardial dysfunction identified at rest or unmasked during exercise. We examined the correlates of the myocardial exercise response in patients with ...JOURNAL ARTICLE -
Application of an exercise intervention on the evolution of diastolic dysfunction in patients with diabetes mellitus efficacy and effectiveness
(Circulation: Heart Failure, 2011)Background-Diastolic dysfunction (DD) is associated with adverse cardiovascular outcomes. We studied the impact of an exercise-based lifestyle intervention on the evolution of DD in patients with type 2 diabetes mellitus ...JOURNAL ARTICLE -
Stroke prevention in atrial fibrillation: An update on current management strategies
(Panminerva Medica, 2013)Stroke attributed to atrial fibrillation (AF) confers significant morbidity and mortality. In the past, warfarin has been the only successful stroke prevention agent available. However, it is often underutilized due to its ...JOURNAL ARTICLE -
Echocardiographic predictors of reverse remodeling after cardiac resynchronization therapy and subsequent events
(Circulation: Cardiovascular Imaging, 2013)Background-Studies of echocardiographic predictors of response after cardiac resynchronization therapy (CRT) have largely involved single parameters. We hypothesized that combining parameters would be more robust and sought ...JOURNAL ARTICLE -
Association of outcome with left ventricular parameters measured by two-dimensional and three-dimensional echocardiography in patients at high cardiovascular risk
(Journal of the American Society of Echocardiography, 2014)Background Left ventricular (LV) ejection fraction (EF) measured by two-dimensional echocardiographic (2DE) imaging is an important correlate of survival. Real-time three-dimensional echocardiographic (3DE) imaging has ...JOURNAL ARTICLE -
Comprehensive dobutamine stress CMR versus echocardiography in LBBB and suspected coronary artery disease
(JACC: Cardiovascular Imaging, 2014)Objectives This study aimed to compare dobutamine stress cardiac magnetic resonance (DSCMR) with dobutamine stress echocardiography (DSE) in patients with left bundle branch block (LBBB) and suspected coronary artery disease ...JOURNAL ARTICLE -
Hemodynamic benefit of rest and exercise optimization of cardiac resynchronization therapy
(Echocardiography, 2014)The optimal method of cardiac resynchronization therapy (CRT) optimization is as yet unknown. We sought to investigate the responses of optimization at rest and on exercise. This 2 stage study involved 59 patients (age 65 ...JOURNAL ARTICLE